CBD Oil Side Effects: What to Know Before You Try CBD Oil

CBD oil and its many benefits have been taking over much of our communication lately. We’ll admit, we’re pretty excited at the many medical conditions that can be helped from just this one supplement.


When we’re able to help our customers find their healthy place, we’re in our happy place.


And we’ll also admit, we’re a little blown away by how safe and effective CBD oil is — and how many of our customers all across the USA are reporting incredible results.


But nothing in life is perfect, right?


In this article, we’re going to explore some of the side effects of CBD oil, whether or not it’s possible to take too much, and what CBD oil can make you feel like. We’ll look at some scientific research and discuss testimonies and reports from CBD oil users.


Let’s jump in!

CBD Oil Side Effects

CBD oil side effects are minor. It is considered to be a ‘safe substance’. Pure CBD oil without THC cannot make you high.


In fact, it’s worth noting that even whole cannabis, or marijuana, is also actually considered to be an extremely safe drug. It’s virtually impossible for an adult human to ingest a fatal dose — although you can definitely make yourself feel extremely sick from using too much of it.


Reported side effects from studies and anecdotal reports from consumers affirm that CBD is a ridiculously safe supplement with very few side effects. But all of our bodies react differently to substances, right?


Here’s a full list of CBD oil side effects that have been reported or documented (according to current research and studies).

  1. Dry Mouth. CBD oil can cause dry mouth. While researchers aren’t completely sure why this can happen, a study published in 2006 showed that the endocannabinoid system receptors CB1 and CB2 are present in the glands responsible for producing saliva. When these receptors are activated, the saliva production can drop, leading to dry mouth. Dry mouth is exactly what it sounds like, and will pretty much do nothing more than prompt you to drink a little more water than normal.
  2. Lower Blood Pressure. High doses of CBD oil can cause a small drop in blood pressure in some individuals. This will usually occur within a few minutes of the CBD oil entering your system. This doesn’t happen to everyone, and the worst you should expect is a few minutes of feeling lightheaded. However, if you have any problems with low or high blood pressure, or are taking any medications for blood pressure, talk to your doctor before trying CBD oil, because this may not be a good fit for you.
  3. Lightheadedness or Dizziness. This is usually connected to low blood pressure, as mentioned in the point above, but some people just feel a little dizzy for a few moments after CBD oil hits their system. This typically passes within a few minutes on its own, or can usually be resolved by laying down for a few moments, drinking a cup of coffee or tea, or snacking on a little piece of chocolate.
  4. Nausea. Some people have found that ingesting CBD oil can cause mild stomach discomfort. This is based off of reports we’ve heard and read, rather than any evidence from scientific studies. This is an odd side effect, considering that CBD oil is used to help relieve nausea and increase appetite. If nausea does occur, it is mild and typically goes away quickly. If you find this happens to you, decrease your dose and it should go away.
  5. Sleepiness or drowsiness. This side effect of CBD oil should hardly come as a surprise, as high doses of CBD oil may be used as a sleep aid for those struggling with insomnia. At low doses, CBD oil causes relaxation and diminished pain or anxiety — both conditions that can contribute to insomnia. At higher doses, it can produce drowsiness. If CBD oil causes drowsiness for you, don’t take CBD oil before operating machinery or driving a vehicle. Remember, CBD oil can sometimes take several hours to kick in.
  6. Increased Tremors in Parkinson’s Disease. If you suffer from Parkinson’s Disease, we recommend speaking to your doctor before trying CBD oil. Early research suggests that one of the side effects of CBD oil, when taken in high doses, is that is may worsen the muscle tremors associated with Parkinson’s Disease. More recent research has indicated that at low doses it may also be safe and helpful for those struggling with this disease. But, because there is some ambiguity on this topic, we strongly suggest consulting your medical practitioner before trying anything.
  7. Headaches. Can CBD oil cause headaches? Yes, and no. CBD oil is used to treat headaches and migraines, and there are hundreds (if not thousands) of people who report that it effectively relieved their pain symptoms. It’s more likely that if you’re experiencing headaches as a side effect of CBD, that the product you’ve purchased is a lower quality CBD, or contains solvents, such as ethanol and isopropanol, which some people are sensitive too. We’d recommend switching to a higher-quality hemp-based CBD oil, and the headache problems should go away. That said, we’ll also admit that all of our bodies are a little bit different, and it may just be that CBD oil isn’t your best fit.


Although medical research on CBD oil and medical marijuana use is still in the beginning stages, thanks to Federal regulatory laws, researchers have devoted some serious effort (and even put their own careers at risk) to prove that CBD oil is not only safe for human consumption but actually a huge benefit.

Can I Overdose On CBD Oil?

Consistent consumption of CBD oil over long periods of time has, so far, showed no health concerns. A study in 2006 reported,


“…Acute CBD administration by the oral, inhalatory or intravenous route did not induce any significant toxic effect in humans. In addition, chronic administration of CBD for 30 days to healthy volunteers, at daily doses ranging from 10 to 400 mg, failed to induce any significant alteration in neurological, psychiatric or clinical exams. Finally, in patients suffering from Huntington’s disease, daily doses of CBD (700 mg) for 6 weeks did not induce any toxicity.”


A later study also showed that chronic use and high doses up to 1,500 mg/day of CBD were well tolerated. This study examined the side effects of CBD oil when consumed daily for a month. It showed that all patients and volunteers tolerated CBD oil very well, and showed no signs of toxicity or adverse side effects.


The conclusion of these studies is that, based on results from animal and human research, clinical data indicates that CBD oil can be safely used over a wide dose range, and over long periods of use. There are no CBD oil withdrawal symptoms, as the system does not become chemically dependent on CBD.


So — our conclusion? When using CBD oil based on use recommendations and reasonable dosages, you don’t need to worry about overdoses or toxicity.*

Can CBD Get You High?

This is one of the questions we hear most often from curious customers — can CBD oil get you high?


Easy, simple answer. No!


CBD oil does contain trace amounts of tetrahydrocannabinol (THC), which is the component found in cannabis that is responsible for creating the ‘high’. However, these levels are 33 times lower than necessary to produce a high. CBD chemically cannot get you high.


We will note that it is important to find a high-quality, pure CBD oil that is hemp-based or appropriately processed. Poor quality CBD oils may contain enough THC to produce an effect. This is easily avoided by choosing quality brands.

What Does CBD Oil Feel Like?

Honestly, it mostly feels like nothing at all — unless you happen to experience CBD oil side effects.


Depending on the reason that you’re taking CBD oil, you may feel any of the following:

  • Increased sense of calm or diminished anxiety
  • Improved mood
  • Reduced pain and diminished discomfort related to inflammation
  • A sense of relaxation, sometimes with a mild ‘loosening’ of the muscles
  • Sleepiness or drowsiness


Basically, the primary way that you’ll ‘feel’ CBD oil is through the relief of the symptoms that you’re taking CBD oil for.

What Drugs Should Not Be Taken With CBD Oil?

Side effects can include some CBD oil drug interactions — specifically, the inhibition of hepatic drug metabolism and decreased activity of p-glycoprotein. In layman’s terms, CBD oil can inhibit the activity of some liver enzymes that are responsible for metabolizing pharmaceutical drugs. High doses of CBD oil can temporarily neutralize these liver enzymes, which affects the way the drugs are used in your body.


To put this into some perspective, eating a grapefruit would have a similar effect.


If you are currently taking any pharmaceutical drugs, we’d suggest speaking to your pharmacist or primary care doctor to discuss any possible complications before taking CBD oil.

How to Choose the Best CBD Oil

Purity, in any supplement, matters more than anything else. In order to see the actual benefits of CBD oil, you must find a great CBD oil product. We’ve done some intense screening on the CBD oil brands we’ve decided to include in our stores, but these aren’t the only great products on the market.


But there ARE a lot of inferior products out there as well. Here are the guidelines you need to follow when buying CBD oil online, rather than from a trusted local nutrition store, dispensary, or medical practitioner.

  1. Always check the purity. It should be more than 50% CBD, or more, with no or only trace amounts of THC.
  2. Always check the source. We’d recommend only buying CBD oil that has been manufactured in Canada, Europe, or the USA. Thanks to some strict regulations, this will help ensure a higher quality product.
  3. Don’t leap for the cheapest CBD oil. Just like everything in life, you’re going to have a pay a little more to get good quality — and it’s worth it. When it comes to your health, it pays to be choosy. Spending more on quality makes sense when spending more means actually seeing benefits.


If you have more questions about CBD oil side effects or CBD oil benefits, we’d love to talk to you further. Give our team of Wellness Consultants a call at 608.571.1094 or drop into any of our store locations.


Let’s find your healthy place!



Disclaimer: We always recommend that you speak with a licensed medical practitioner before modifying, stopping, or starting use of any medications and supplements. The statements made on this page have not been evaluated by the U.S. Food and Drug Administration (FDA). They are not intended to diagnose, cure or prevent any disease. If a condition persists, please contact your physician or healthcare provider. The information provided is not a substitute for a face-to-face consultation with a healthcare provider, and should not be construed as medical advice.



Apple Wellness – The Healthy Place

6313 McKee Road, Fitchburg, WI  53719


2824 Prairie Lakes Drive, Sun Prairie, WI  53590




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  1. This is a great review. CBD has a therapeutic window in which it is most effective for people. Therapeutic ranges vary from person to person so it’s important to start with low doses.
    Side efects mentioned in this review are more likely encountered when people take higher doses of CBD. Variations can also result from bioavailability and route of administration. For instance, nasal administration results in much higher brain levels than transdermal, or oral applications of equivalent amounts, so less CBD is needed when taken nasally.

      1. Hi Lindsey,

        Sorry to hear that CBD didn’t prove to be the solution we were hoping for. Remember that our return policy guarantees products, so bring your bottle back into the store and we’ll give you full in-store credit. We’d be happy too, to help you keep looking for a solution. You are 100% right — CBD isn’t a miracle cure-all, and because we’re all different, CBD works great for many people, but not for everyone. Stop back in — we’re here to help!

      2. Me too! Mine is definitely pure and high quality and no solvents are used. Only MCT oil is used to pull the CBD out. It gives me a horrible headache. Thankful for this article giving me some answers though. Doesn’t help with my pain either. Just with my sleep. And is it possible that it’s preventing electrolyte absorption?

  2. I’m currently taking CBD oil that is full spectrum with natural cannabinoids and terpenes, produced from the c sativa bloom, the company assured me it’s good, I don’t know if I’m not taking g enough, I feel more relaxed, but alot of my pain still remains, please give me your feedback please.

    1. Hi Vicki,

      We’d be happy to talk to you about your dosage to see if we can address that pain issue. Why don’t you give our Wellness Consultants and call and we can have a sit-down conversation with you to troubleshoot the issue. 608-663-2640 Look forward to hearing from you!

  3. I have tried Symmetry CBD 10 & 5 drops make me feel jittery and I am not sure when I thought it should help calm my anxiety and thoughts?

    1. Hi Mandy,

      That’s an unusual response for CBD, but we are all different! It may be that changing the brand could be helpful, or we may want to change your dosage further. Why don’t you stop by the store or give us a call to connect with one of our Wellness Consultants? We’d be delighted to help you figure out the best solution. Here’s our contact info!


    2. Mandy, I believe your results are not all that unsual, but not very popular right now as people are looking for answers they couldnt find elsewhere and hope. Unfortuately i have given it to my anxious dog twice now and a year apart sold by two different companies. The second being a more reputable and a higher quality organic company. Both times my dog became increasingly MORE agressive to other dogs. I had to stop. I dont see anyone else put there who have had similar results. I think people should be made awhere (as you said) everyone is different and will not be guaranteed the same results.

  4. I was taking THC and CBD oil for pain and developed stomach pain so bad that I thought I had pancreatitis. It was the worst pain of my life and lastest about an hour. I had previous stomach discomfort from the oil but this last bout has kept me from ever wanting to try it again. I can’t vape or smoke because I about choke to death and edibles aren’t legal in our state so I’m off of the marijuana and back to opioids unfortunately. I did have gastric bypass surgery 10 years ago – I suppose its possible it make me more sensitive.

  5. Can CBD cause exesive night sweating? I have give some drops to my Mom (91 yrs old) and notice she needs to be changed many times at night as she sweats a lot. I had not noticed this before taking the drops.

    1. Hi Jorge,

      Great question. We’ve never encountered anyone developing night sweats from CBD oil. In fact, some people use it to help diminish symptoms of menopause, including hot flashes. However, that being said, we are all different. We’d recommend adjusting the dose or stopping temporarily to see if that affects her night sweats. Why don’t you give our Wellness Consultants a call — we’d be happy to talk it through with you! 608-663-2640

  6. Hi Cynthia,
    Great question! We would recommend that your father consults with a licensed medical professional regarding this. CBD is not a blood thinner, but it can interact with medications and affect blood pressure, etc. Definitely check with your health care provider!

    1. Hi Pat,

      Great question! CBD can cause nausea for some individuals, particularly when they’re taking high doses. It’s odd, as CBD is also used to help people struggling with nausea and low appetite. We’re all a little different, so the responses vary too. If you’re experiencing nausea, consider taking it with food or backing down on the dose. If you want to chat with someone on our team, feel free to call us at any point or swing by one of the stores. We’re here to help!

  7. Ooh, this is helpful! I use CBD oil for my dogs, to help them with reactivity. It’s tough not knowing how they are feeling because they can’t tell me if they are experiencing side effects, but we do get it from a source that grows their own hemp plants, and it’s organic. We haven’t been using it for very long, but I do notice a calming effect about 30 minutes after they take it. I’m going to make sure they have something to drink afterwards like broth or goat’s milk to combat dry mouth.

    1. Hi Lindsay,

      That’s awesome! Glad to hear you’ve found a good option for your pups. I use it for mine and it works really well for chilling out our more hyper furry family member. If you run into any questions, just reach out. We’re here to help!

    1. Hi Risemarie,

      I’m not sure about that, so I’ve passed along your information to one of our Wellness Consultants. He’ll be reaching out to you via email to work through that question! You should hear from him shortly.

  8. Im a cancer patient diagnose tripple negative breast cancer stage 3.Done all my 6cycles of chemotherapy.From 11cm my tumour finally it has shrink to1cm.But still doctor said have to remove my one side breast and also my lymph nodes under my armpit. Surgical doctor has planned my operation datw and that is when i heard about this CBD oil. I request to my surgical doctor to postpone my operation meanwhile to try taking this oil.My first trying of this CBD oil 20% on 14Nov2018 night dose 12 before bed and 6dose in the morning before breakfast i dont have any side effects execpt of dry mouth.I even dont feel drowzy or anything infact after this dosage i still can go to gym for workout.I dont feel anything and is this ok???

    1. Hi Vidya,

      I’m so sorry that you’re going through this. To answer your question, not feeling a ‘reaction’ to CBD is the most common response. The results build up over time.

      Because you’re in the midst of a serious health issue, I’d urge you to have a one-one conversation with our Wellness Consultants so that we can make sure we’re making recommendations and giving input that is accurate and helpful for your situation. If you reach out to us, we’d be happy to work with you and your medical doctor to step alongside you in this however we can. https://apple-wellness.com/contact/

  9. I’m taking lofrapamine an antidepressant for the last three weeks I’ve bought some canabidol tablets 300 mg to try would they interact with them

    1. Hi Debbie,

      We should have you have a one-one chat with our Wellness Consultants. I’ve passed along your information and we’ll be reaching out to you via email to work through that question! Stay tuned!

  10. The first time I came across CBD was when I was visiting my brother in San Antonio, Texas 2 years back. The one day I had some serious back pain, My brother’s neighbour suggested that I should try CBD oil for my pain as it helps his mom with her cancer pain, and directed me to a local CBD shop in San Antonio where I bought a 2000mg CBD oil. In the beginning, I was a sceptic, but it worked so well that I ordered three more bottles to last me for a few months. I must say that also felt relaxed but could do my work with no issues as it didn’t make me high. To date, I’m still using CBD oil for my pain and came off pain medications completely.

  11. I started to take CBD after I had a hard time sleeping due to bursitis in the shoulder. My trips to physical therapy only aggravated the pain issues from inflammation. My doctor and PT prescribed ibuprofen but when I used their prescribed dosage, it caused me more gastric problems than normal. Since using CBD sublingual at 5 drops of 300 mg at night, it seemed to help me get through the night and I stopped completely the use of over the counter pain relievers. An added unexpected benefit of daily nightly CBD use, was that my Gerd symptoms (that I had for years) disappeared and allowed me to stop taking Prilosec daily. For pain during the day, I use CBD as needed. I think CBD is a great natural alternative to pills. All in all, I am very pleased with CBD and expect to continue to use it moving forward. I am 68 years old and I believe that CBD for me at my age is a great thing!.

  12. So I got an ignite CBD disposable vape pen and I just took my first hit and the sides of my head in the front like both of my temples feel really weird and it’s a very uncomfortable feeling like I’m kinda freaking out. Idk if it’s bad or not but there are also some essential oils in the vape also. Please help quick. I wanna know if I’m okay and if this is normal and if it will go away.

    1. Hi P,

      That is definitely a very unusual response to CBD — it sounds like maybe you’re reacting to one of the ingredients in the pen. It’s possible that you’re sensitive to CBD, but it could be the pen and quality of ingredients in that. I would urge you to stop taking CBD immediately. Why don’t you give us a call when you’ve got a free moment and talk through your experience with one of our Wellness Consultants? They’ll be able to provide some additional guidance after chatting with you.

  13. I smoked before bed and feel asleep but when I woke up it felt like I was dizzy going to pass out with no oxygen to my brain and I had a tingling sensation in my head is that normal ?? Can CBd increase ur anxiety ?

    1. Hi Julisa,

      That would be a very unusual response. CBD can make you feel dizzy, but this is usually very brief and promptly after taking it. It’s also possible that you’re using a contaminated CBD brand. With the recent boom in popularity, there are quite a few poor quality products circulating out there.

      It sounds like you’re smoking CBD buds, not using softgels, drops, or vapes such as those we sell in our stores. Is that right? Why don’t you give our Wellness Consultants a call and we can talk through what you’ve been using and if there’s another option that can have less unpleasant results for you. https://apple-wellness.com/contact/

  14. Apperently cbd oil makes my foot fall asleep.
    Can’t feel my foot it unltill i’ve been clean from cbd for a week… Is that normal? Any explanation to why this is happening?

    1. Hi Benjamin,

      That is definitely a very unusual response to CBD. I would urge you to stop taking CBD immediately. In the meantime, I’d suggest giving us a call when you’ve got a free moment and talking through this with one of our Wellness Consultants. https://apple-wellness.com/contact/


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